Highly Selective and Prolonged Depletion of Mitochondrial Glutathione in Astrocytes Markedly Increases Sensitivity to Peroxynitrite Journal of Neuroscience Interleukin 4 deficiency protects mice from acetaminophen induced liver injury and inflammation by prevention of glutathione depletion Inflammation Research Springer Nature Link There are many studies showing low Glutathione levels with Parkinson's and Alzheimer's disease. Also several studies show low glutathione is considered to be one of the early biochemical changes in both Parkinson's Figure 1 from Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors. Semantic Scholar Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells Cell Death & Disease